Molecular mechanisms and applications of tea polyphenols: A narrative review (2025)

Journal of Food Biochemistry

Volume 45, Issue 10 e13910

REVIEW

Yan Chen,

Yan Chen

State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, China

School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Contribution: Writing - original draft

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Si Cheng,

Si Cheng

School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Contribution: Writing - review & editing

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Jiangang Dai,

Jiangang Dai

School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Contribution: Writing - review & editing

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Liang Wang,

Liang Wang

School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Contribution: Writing - review & editing

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Yun Xu,

Yun Xu

School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Contribution: Writing - review & editing

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Xiaoyu Peng,

Xiaoyu Peng

School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Contribution: Writing - review & editing

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Xiaofang Xie,

Corresponding Author

Xiaofang Xie

  • [emailprotected]

State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, China

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Correspondence

Xiaofang Xie and Cheng Peng, State Key Laboratory of Southwestern Chinese Medicine Resources, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Emails: [emailprotected] (X. X.); [emailprotected] (C. P.)

Contribution: Writing - review & editing

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Cheng Peng,

Corresponding Author

Cheng Peng

  • [emailprotected]

State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, China

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Correspondence

Xiaofang Xie and Cheng Peng, State Key Laboratory of Southwestern Chinese Medicine Resources, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Emails: [emailprotected] (X. X.); [emailprotected] (C. P.)

Contribution: Writing - review & editing

Search for more papers by this author

Yan Chen,

Yan Chen

State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, China

School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Contribution: Writing - original draft

Search for more papers by this author

Si Cheng,

Si Cheng

School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Contribution: Writing - review & editing

Search for more papers by this author

Jiangang Dai,

Jiangang Dai

School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Contribution: Writing - review & editing

Search for more papers by this author

Liang Wang,

Liang Wang

School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Contribution: Writing - review & editing

Search for more papers by this author

Yun Xu,

Yun Xu

School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Contribution: Writing - review & editing

Search for more papers by this author

Xiaoyu Peng,

Xiaoyu Peng

School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Contribution: Writing - review & editing

Search for more papers by this author

Xiaofang Xie,

Corresponding Author

Xiaofang Xie

  • [emailprotected]

State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, China

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Correspondence

Xiaofang Xie and Cheng Peng, State Key Laboratory of Southwestern Chinese Medicine Resources, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Emails: [emailprotected] (X. X.); [emailprotected] (C. P.)

Contribution: Writing - review & editing

Search for more papers by this author

Cheng Peng,

Corresponding Author

Cheng Peng

  • [emailprotected]

State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, China

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Correspondence

Xiaofang Xie and Cheng Peng, State Key Laboratory of Southwestern Chinese Medicine Resources, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Emails: [emailprotected] (X. X.); [emailprotected] (C. P.)

Contribution: Writing - review & editing

Search for more papers by this author

First published: 23 August 2021

Citations: 42

Abstract

Tea is a worldwide popular drink with high nutritional and medicinal values as it is rich in nutrients, such as polyphenols, amino acids, vitamins, glycosides, and so on. Among them, tea polyphenols (TPs) are the current research hotspot. TPs are known to have multiple biological activities such as anti-oxidation, anti-tumor, anti-inflammation, anti-bacteria, lowering lipid, and liver protection. By reviewing a large number of literatures, we explained the mechanism of TPs exerting biological activity and a wide range of applications. We also discussed the deficiencies and development potential of TPs, in order to provide theoretical reference and scientific basis for the subsequent development and utilization of TPs.

Practical applications

We summarized the bioactivity mechanisms of TPs in anti-tumor, anti-oxidation, antibacterial, anti-inflammatory, lipid-lowering, and liver protection, focused on its application fields in food and medicine, and discussed the deficiency and development potential of current research on TPs, so as to provide a certain convenient way for scholars studying TPs. It is expected to contribute to the subsequent discovery of biological activity and the broadening of the field of TPs.

CONFLICT OF INTEREST

The authors declare no conflict of interest.

Open Research

The data is available.

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Molecular mechanisms and applications of tea polyphenols: A narrative review (2025)
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